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lps d galn  (MedChemExpress)


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    MedChemExpress lps d galn
    Lps D Galn, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 664 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lps+d+galn/pm39904423-139-19-30?v=MedChemExpress
    Average 99 stars, based on 664 article reviews
    lps d galn - by Bioz Stars, 2026-08
    99/100 stars

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    The preventive ( A , B ) and therapeutic ( C , D ) effects of PT extract on acute liver injury after <t>D-GalN/LPS</t> injection. ( A , B ) C57BL/6J mice were administered HD and PT orally for 3 days and then received intraperitoneal D-GalN (450 mg/kg) and LPS (10 μg/kg) after fasting overnight. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( A ) and ALT ( B ). ( C , D ) The mice received D-GalN and LPS via intraperitoneal injection after fasting overnight and were then administered HD and PT orally. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( C ) and ALT ( D ). The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significances of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.
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    lps and d-galn  (Beyotime)
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    The preventive ( A , B ) and therapeutic ( C , D ) effects of PT extract on acute liver injury after <t>D-GalN/LPS</t> injection. ( A , B ) C57BL/6J mice were administered HD and PT orally for 3 days and then received intraperitoneal D-GalN (450 mg/kg) and LPS (10 μg/kg) after fasting overnight. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( A ) and ALT ( B ). ( C , D ) The mice received D-GalN and LPS via intraperitoneal injection after fasting overnight and were then administered HD and PT orally. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( C ) and ALT ( D ). The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significances of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.
    Lps And D Galn, supplied by Beyotime, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    The preventive ( A , B ) and therapeutic ( C , D ) effects of PT extract on acute liver injury after D-GalN/LPS injection. ( A , B ) C57BL/6J mice were administered HD and PT orally for 3 days and then received intraperitoneal D-GalN (450 mg/kg) and LPS (10 μg/kg) after fasting overnight. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( A ) and ALT ( B ). ( C , D ) The mice received D-GalN and LPS via intraperitoneal injection after fasting overnight and were then administered HD and PT orally. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( C ) and ALT ( D ). The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significances of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.

    Journal: International Journal of Molecular Sciences

    Article Title: Ethanol Extract of the Microalga Phaeodactylum tricornutum Shows Hepatoprotective Effects against Acetaminophen-Induced Acute Liver Injury in Mice

    doi: 10.3390/ijms25116247

    Figure Lengend Snippet: The preventive ( A , B ) and therapeutic ( C , D ) effects of PT extract on acute liver injury after D-GalN/LPS injection. ( A , B ) C57BL/6J mice were administered HD and PT orally for 3 days and then received intraperitoneal D-GalN (450 mg/kg) and LPS (10 μg/kg) after fasting overnight. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( A ) and ALT ( B ). ( C , D ) The mice received D-GalN and LPS via intraperitoneal injection after fasting overnight and were then administered HD and PT orally. After 6 h, the mice were sacrificed, and their blood was collected for serum separation. Sera were separated from blood for AST ( C ) and ALT ( D ). The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significances of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.

    Article Snippet: In the case of PT therapeutic activity ( D), the animals received D-GalN/LPS (Sigma Aldrich) via intraperitoneal injection after fasting overnight for approximately 15 h. After 24 h, the mice were sacrificed, their blood was collected, and their livers were removed.

    Techniques: Injection

    Histological analysis of liver tissues. Liver tissue sections of normal and D-GalN/LPS-injected mice stained with H&E are shown (magnification, 200× and 400×). ( A ) H&E staining images; ( B ) grayscale images converted with ImageJ; ( C ) percentage of area of extravasated RBCs in the image. The significance of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.

    Journal: International Journal of Molecular Sciences

    Article Title: Ethanol Extract of the Microalga Phaeodactylum tricornutum Shows Hepatoprotective Effects against Acetaminophen-Induced Acute Liver Injury in Mice

    doi: 10.3390/ijms25116247

    Figure Lengend Snippet: Histological analysis of liver tissues. Liver tissue sections of normal and D-GalN/LPS-injected mice stained with H&E are shown (magnification, 200× and 400×). ( A ) H&E staining images; ( B ) grayscale images converted with ImageJ; ( C ) percentage of area of extravasated RBCs in the image. The significance of the differences between the value of the D-GalN/LPS group and that of the HD and PT treatment groups after D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: ** p < 0.01.

    Article Snippet: In the case of PT therapeutic activity ( D), the animals received D-GalN/LPS (Sigma Aldrich) via intraperitoneal injection after fasting overnight for approximately 15 h. After 24 h, the mice were sacrificed, their blood was collected, and their livers were removed.

    Techniques: Injection, Staining

    Effect of PT on the production of inflammatory cytokines in acute liver failure mouse models. Sera obtained from acetaminophen ( A , B ) and D-GalN/LPS ( C , D ) animal models were used in ELISA assays for TNF-α and IL-1β. The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significance of the differences between the value of AP or D-GalN/LPS groups and that of the SM, HD, and PT treatment groups after AP or D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: * p < 0.05 and ** p < 0.01.

    Journal: International Journal of Molecular Sciences

    Article Title: Ethanol Extract of the Microalga Phaeodactylum tricornutum Shows Hepatoprotective Effects against Acetaminophen-Induced Acute Liver Injury in Mice

    doi: 10.3390/ijms25116247

    Figure Lengend Snippet: Effect of PT on the production of inflammatory cytokines in acute liver failure mouse models. Sera obtained from acetaminophen ( A , B ) and D-GalN/LPS ( C , D ) animal models were used in ELISA assays for TNF-α and IL-1β. The data from three independent experiments, each of which was performed in triplicate, are indicated as the mean ± SD. The significance of the differences between the value of AP or D-GalN/LPS groups and that of the SM, HD, and PT treatment groups after AP or D-GalN/LPS injection were determined through one-way ANOVA with Tukey’s comparisons test: * p < 0.05 and ** p < 0.01.

    Article Snippet: In the case of PT therapeutic activity ( D), the animals received D-GalN/LPS (Sigma Aldrich) via intraperitoneal injection after fasting overnight for approximately 15 h. After 24 h, the mice were sacrificed, their blood was collected, and their livers were removed.

    Techniques: Enzyme-linked Immunosorbent Assay, Injection

    Outline of the experimental design for the in vivo study of the preventive ( A ) and therapeutic ( B ) effects of PT extract on acetaminophen-induced acute liver injury and the preventive ( C ) and therapeutic ( D ) effects of PT extract on D-GalN/LPS-induced acute liver injury.

    Journal: International Journal of Molecular Sciences

    Article Title: Ethanol Extract of the Microalga Phaeodactylum tricornutum Shows Hepatoprotective Effects against Acetaminophen-Induced Acute Liver Injury in Mice

    doi: 10.3390/ijms25116247

    Figure Lengend Snippet: Outline of the experimental design for the in vivo study of the preventive ( A ) and therapeutic ( B ) effects of PT extract on acetaminophen-induced acute liver injury and the preventive ( C ) and therapeutic ( D ) effects of PT extract on D-GalN/LPS-induced acute liver injury.

    Article Snippet: In the case of PT therapeutic activity ( D), the animals received D-GalN/LPS (Sigma Aldrich) via intraperitoneal injection after fasting overnight for approximately 15 h. After 24 h, the mice were sacrificed, their blood was collected, and their livers were removed.

    Techniques: In Vivo

    Experimental groups in D-GalN/LPS—induced acute liver injury model.

    Journal: International Journal of Molecular Sciences

    Article Title: Ethanol Extract of the Microalga Phaeodactylum tricornutum Shows Hepatoprotective Effects against Acetaminophen-Induced Acute Liver Injury in Mice

    doi: 10.3390/ijms25116247

    Figure Lengend Snippet: Experimental groups in D-GalN/LPS—induced acute liver injury model.

    Article Snippet: In the case of PT therapeutic activity ( D), the animals received D-GalN/LPS (Sigma Aldrich) via intraperitoneal injection after fasting overnight for approximately 15 h. After 24 h, the mice were sacrificed, their blood was collected, and their livers were removed.

    Techniques: Injection